The Relationship of Shear Wave Elastography Findings With Pain Threshold and Quality of Life in Patients With Lipedema

Fatih Sultan Mehmet Training and Research Hospital

Status: Completed

Conditions: Lipedema; Pain

Treatments: Diagnostic Test: SWE:B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography at three level

Study type: Observational

Funder types: Other

Identifiers

NCT06196619

gulcanozturkchatip

Details and patient eligibility

About

The aim of this study is to evaluate the relationship between disease severity and subcutaneous tissue shearwave elastography findings with pain threshold and quality of life in patients diagnosed with lipedema.

Full description

Patients diagnosed with lipedema were divided into 3 stages according to disease severity. Pain level was evaluated with visual analogue scale, pain threshold with algometric measurement, and quality of life with EQ-5D general quality of life scale. All patients underwent measurements using B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography (SWE) imaging of lower limbs at three anatomical levels.

Enrollment: 70 patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female patients diagnosed with lipedema

Exclusion criteria

• under 18 years of age,
• Patients with edema of cardiac or nephrogenic origin, diabetes mellitus, thyroid dysfunction, patients with lymphedema or chronic venous insufficiency, oncology patients,
• individuals with polyneuropathy, radiculopathy, or advanced degenerative diseases affecting the extremities within the last 6 months, based on clinical findings and medical history.
• patients using antiepileptics and antidepressants,
• individuals unable to cognitively tolerate participation in the study were also excluded.

Trial design

70 participants in 3 patient groups

Stage 1 lipedema patients

Description:

It is the stage where normal skin surface, enlarged subcutaneous fat tissue, and many small nodules are present upon palpation.

Treatment:

Diagnostic Test: SWE:B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography at three level

Stage 2 lipedema patients

Description:

It is the stage with rough skin surface, large nodules of palpable subcutaneous fat tissue

Treatment:

Diagnostic Test: SWE:B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography at three level

Stage 3 lipedema patients

Description:

It is the stage in which lobular deformation of the skin surface occurs with enlarged fatty tissue.

Treatment:

Diagnostic Test: SWE:B-mode ultrasound and subcutaneous elastic modulus with shear wave elastography at three level