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The Reliability and Validity of the L-test in Patients With Multiple Sclerosis

G

Gazi University

Status

Completed

Conditions

Multiple Sclerosis

Treatments

Other: The timed 360° turn test
Other: 10 meter walk test
Other: Six Minute Walk Test
Other: Timed Up and Go test
Other: L test

Study type

Observational

Funder types

Other

Identifiers

NCT05641714
1-MS-L-Test-reliability

Details and patient eligibility

About

Walking safely inside or outside is an important function in patients with Multiple Sclerosis (PwMS) that affects their daily life activity and participation. Loss of functional mobility is the major component of walking disorders in PwMS. Therefore, it is important to evaluate functional mobility.

Many functional mobility tests have been used for PwMS; however, these tests generally focus on walking speed and endurance. On the other hand, the L test, a variation of the timed up and go test (TUG), is a functional mobility measurement tool that extends the total walking distance to 20 meters and also requires the patients to turn both clockwise and counterclockwise.

Although L the test is an easy-to-use, short-term test method that evaluates higher-level components of functional mobility such as turns and transfers, to our knowledge, no study has systematically examined the reliability and validity of the L test in PwMS yet. In addition, the cut-off times that best discriminate PwMS from healthy people and fallers with non-fallers with Multiple Sclerosis (MS) have not been reported. Therefore, this study planned to investigate the reliability, validity, and discrimination of the L test in PwMS.

Full description

At baseline, the L test, Timed Up and Go test, 10 meter walk test, six minute walk test, and the timed 360 turn test will be applied to the Multiple Sclerosis group. The L test will be repeated after seven days after the first application in PwMS. Healthy controls are going to perform only the L test.

Enrollment

68 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Age at least 18 years,
  • Neurologist-diagnosed Multiple Sclerosis,
  • Expanded Disability Status Scale (EDSS) score between 0-5,
  • No MS exacerbation within the last 3 months,
  • Use of stable medication in the last 3 months.

Exclusion criteria

  • Having any vision, hearing, or perception problems that may affect the research results,
  • Having an orthopedic problem that will prevent walking and standing
  • Having a cardiovascular, pulmonary, or hormonal disorder

Trial design

68 participants in 2 patient groups

multiple sclerosis
Description:
Patients with Multiple Sclerosis
Treatment:
Other: Six Minute Walk Test
Other: L test
Other: The timed 360° turn test
Other: 10 meter walk test
Other: Timed Up and Go test
healthy controls
Description:
healthy controls
Treatment:
Other: L test

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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