The Reproducibility and Clinical Utility of an Abbreviated Fat Tolerance Test

Oklahoma State University

Status: Completed

Conditions: Dyslipidemias; Metabolic Syndrome

Treatments: Other: High-fat shake; Other: Pure glucose solution

Study type: Interventional

Funder types: Other

Identifiers

NCT04437459

HS1844

Details and patient eligibility

About

This study aims to evaluate the reliability of a shortened fat tolerance test ("abbreviated fat tolerance test", or "AFTT") for measuring post-meal lipids in human blood. The reliability of the triglyceride results in this test are compared to the reliability of the glucose results from an oral glucose tolerance test (OGTT), a widely-used and clinically accepted metabolic test.

Enrollment: 22 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Free of chronic disease
• Normal (healthy) fasting glucose and triglycerides

Exclusion criteria

• Presence of pace-maker
• Pregnant
• Using tobacco products
• Using medications or dietary supplements that could modify primary outcomes

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

22 participants in 2 patient groups

Abbreviated Fat Tolerance Test

Experimental group

Treatment:

Other: High-fat shake

Oral Glucose Tolerance Test

Active Comparator group

Treatment:

Other: Pure glucose solution