The Research of the Effect of Sevoflurane on Brain-protection of Cardiac Surgery in Infants.

Jun Ma

Status: Unknown

Conditions: Infant, Premature, Diseases; Congenital Heart Disease

Treatments: Drug: Sevoflurane

Study type: Interventional

Funder types: Other

Identifiers

NCT03366597

2017030X

Details and patient eligibility

About

To observe the effect of sevoflurane on the concentration of S100β and regional cerebral oxygen saturation in infants with congenital heart disease undergoing cardiac surgery.

Enrollment: 100 estimated patients

Sex: All

Ages: Under 3 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of congenital heart disease
• Undergoing heart surgery with cardiopulmonary bypass

Exclusion criteria

• Pulmonary arterial hypertension
• Sevoflurane allergy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

Sevoflurane

Experimental group

Description:

Sevoflurane will be used as a narcotic drug in one group during cardiac surgery.

Treatment:

Drug: Sevoflurane