The Robot-Assisted Laparoscopic Radical Prostatectomy Combined Anterior and Posterior Approach

Nanjing University School of Medicine

Status: Completed

Conditions: Prostatectomy; Prostate Neoplasm

Treatments: Procedure: the robot-assisted laparoscopic radical prostatectomy

Study type: Observational

Funder types: Other

Identifiers

NCT06020287

NanjingUSM202388

Details and patient eligibility

About

The goal of this observational study was to compare the perioperative outcomes, postoperative urinary control rates and positive surgical margin (PSM) rates of the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach (AP-RARP) with the Retzius-sparing approach (RS-RARP) and anterior approach (anterior-RARP) in the treatment of prostate cancer. The main question it aims to answer was:

• The early therapeutic efficacy of the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach

Participants has been underwent:

• AP-RARP
• RS-RARP
• anterior-RARP Researchers compared the three groups to see if AP-RARP combines the advantages of anterior and posterior RARP and is a feasible surgical option for the treatment of prostate cancer.

Enrollment: 233 patients

Sex: Male

Volunteers: No Healthy Volunteers

Inclusion criteria

• pathologically diagnosed with prostate cancer by prostate biopsy
• underwent robot-assisted laparoscopic surgery
• the surgery performed by Weidong Gan
• the extended pelvic lymphadenectomy (PLA) is performed on patients with high-risk prostate cancer (PSA≥20 ng/ml or Grade Group 4-5 or clinical stage ≥T2c) and those considered to have a possibility of lymph node metastasis based on imaging evaluation.

Exclusion criteria

• Patients with a clinical and pathological TNM stage ≥T3b and N1
• patients with distant metastasis
• urinary incontinence before surgery
• received neoadjuvant therapy before surgery

Trial design

233 participants in 3 patient groups

AP-RARP

Description:

the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach

Treatment:

Procedure: the robot-assisted laparoscopic radical prostatectomy

RS-RARP

Description:

the robot-assisted laparoscopic radical prostatectomy with the Retzius-sparing approach

Treatment:

Procedure: the robot-assisted laparoscopic radical prostatectomy

anterior-RARP

Description:

he robot-assisted laparoscopic radical prostatectomy with anterior approach

Treatment:

Procedure: the robot-assisted laparoscopic radical prostatectomy