The Role of Carotid Flow Time-Based Fluid Administration in Caesarean Section

Çukurova University

Status: Completed

Conditions: Cesarean Section; Spinal Anesthesia

Treatments: Device: Corrected carotid flow time measurement guided fluid preload

Study type: Observational

Funder types: Other

Identifiers

NCT06048497

FTCCS

Details and patient eligibility

About

It has been reported that corrected carotid flow time (FTc) may indicate the responsiveness of spontaneously breathing patients to fluid therapy. The primary objective of the study is to determine the effect of fluid preload applied to patients with preanesthetic FTc values below the cut-off value on the incidence of hypotension in cesarean section (C/S) surgery. Pregnant women who underwent cesarean section under spinal anesthesia were included in this prospective study. In the preoperative care unit, patients were assigned to two groups according to their baseline FTc values. Patients with baseline FTc < 327 ms were assigned to the first group, and Ringer Lactate (RL) preload fluid administration to these patients was continued until FTc > 327 ms. On the other hand, patients with baseline FTc > 327 ms were assigned to the second group, and preload fluid was not administered to these patients. Intraoperative hemodynamic data were recorded for each patient.

Enrollment: 72 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 20-40 years of age pregnant women
• American Society of Anesthesiologists (ASA) physical status-II patients
• Uncomplicated, singleton, term pregnancy
• Elective C/S surgery

Exclusion criteria

• Placental disorders
• Gestational hypertensive disorders
• Morbid obesity (BMI>39 kg/m2)
• Carotid stenosis more than 50%
• Baseline SAP more than 160 mmHg
• Arrhythmia
• History of cardiovascular or cerebrovascular disease, and chronic kidney disease (estimated glomerular filtration rate <60 mL/min/1.73 m2)
• Emergency surgery

Trial design

72 participants in 2 patient groups

Preload

Description:

Patients with baseline FTc \< 327 ms were assigned to the preload group, and Ringer Lactate (RL) preload fluid administration to these patients was continued until FTc \> 327 ms.

Treatment:

Device: Corrected carotid flow time measurement guided fluid preload

Non-preload

Description:

Patients with baseline FTc \> 327 ms were assigned to the non-preload group, and preload fluid was not administered to these patients