The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control

R

Rambam Health Care Campus

Status

Completed

Conditions

Healthy

Treatments

Drug: Duloxetine

Study type

Interventional

Funder types

Other

Identifiers

NCT00660751
DNIC01CTIL

Details and patient eligibility

About

The role of central serotonergic and adrenergic systems in the effectiveness of DNIC (Diffuse Noxious Inhibitory Control) will be tested before and after taking Duloxetine and Placebo in a double blind study.

Enrollment

64 patients

Sex

All

Ages

18 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy volunteers
  • age 18-80
  • no chronic disease

Exclusion criteria

  • Subjects who suffer from chronic pain / pain syndrome
  • use of anti-depressant or anti-psychotic drugs
  • food/ drugs sensitivity
  • breast feeding

Trial design

64 participants in 2 patient groups, including a placebo group

1
Active Comparator group
Treatment:
Drug: Duloxetine
2
Placebo Comparator group
Treatment:
Drug: Duloxetine

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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