The Role of CGRPand Nociceptin in Migraine

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National Taiwan University

Status

Unknown

Conditions

Migraine
Headache

Study type

Observational

Funder types

Other

Identifiers

NCT00155129
9361701099

Details and patient eligibility

About

The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.

Full description

The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.

Sex

All

Ages

3 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: patients with headache -

Exclusion Criteria: fever, congenital anomaly, CNS organic lesions

-

Trial contacts and locations

1

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Central trial contact

Pi-Chuan Fan, MD; Li-Chu Chiou, PhD

Data sourced from clinicaltrials.gov

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