The Role of Different Imaging Methods in the Diagnosis of Gallbladder Polyps

Shanghai Jiao Tong University

Status: Unknown

Conditions: Polyp of Gallbladder

Treatments: Device: Abdominal high resolution CT; Device: Contrast-enhanced ultrasonography (CEUS); Procedure: Cholecystectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT02762227

RenJiH

Details and patient eligibility

About

This prospective cohort study is designed to investigate and to compare the diagnostic performance of contrast-enhanced ultrasonography (CEUS) and multidetector computed tomography (CT) for gallbladder cholesterol polyps, adenoma and gallbladder cancer.

Full description

In this study, investigators aimed to investigate the diagnostic performance of CEUS and high resolution CT (HRCT) for the preoperative differential diagnostic accuracies of gallbladder polypoid lesions.

Enrollment: 500 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients with a gallbladder polypoid lesion visited our department, diagnosed by conventional transabdominal US.

Exclusion criteria

• Gallbladder polyp with a diameter less than 10 mm.
• Lesions highly suspected to be cancer due to visible metastasis.
• Allergy to contrast agents and cannot received CT or CEUS examination.
• Women in pregnancy or lactation.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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500 participants in 1 patient group

gallbladder polyps patients

Experimental group

Description:

All patients with a gallbladder polypoid lesion visited our department, diagnosed by conventional transabdominal US, were enrolled in this study. Of these patients, we excluded: (1) gallbladder polyp with a diameter less than 10 mm. (2) lesions highly suspected to be cancer due to visible metastasis. (3) allergy to contrast agents and cannot received CT or CEUS examination. (4) women in pregnancy or lactation. All patients received transabdominal US, abdominal high resolution CT and contrast-enhanced ultrasonography (CEUS) before the cholecystectomy.

Treatment:

Procedure: Cholecystectomy

Device: Contrast-enhanced ultrasonography (CEUS)

Device: Abdominal high resolution CT