The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation

Armed Forces Capital Hospital, Republic of Korea

Status: Completed

Conditions: Tuberculosis

Study type: Observational

Funder types: Other

Identifiers

NCT00889759

TBoutbreak

Details and patient eligibility

About

The aim of this study is to evaluate the role of high-resolution computed tomography of the chest (HRCT) in the investigation of an outbreak of TB that developed in the South Korean army.

Full description

Outbreak investigation including tuberculin skin test (TST), QuantiFERON® TB Gold In-Tube (QFT), and simple chest radiography (CXR) will be performed. For participants with any abnormal findings in these tests, HRCT will be carried out. Active pulmonary TB is diagnosed based on sputum studies or HRCT findings. In addition, participants with positive results both in TST and QTF will be treated as having a latent TB infection (LTBI). TST and QTF were repeated in participants with positive result in one of these tests. CXR will be repeated in all participants at 3 and 6 months of follow-up.

Enrollment: 92 patients

Sex: Male

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All soldiers who assigned to the military battery where a tuberculosis outbreak occurred

Exclusion criteria

• Soldiers who could not complete study