The Role of ITGAM in Systemic Lupus Erythematosus

Northwell Health

Status: Completed

Conditions: Systemic Lupus Erythematosus

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT01230112

09-289

Details and patient eligibility

About

Study to examine the role of ITGAM molecule in normal control subjects with known genetic variation in the ITGAM gene.

Enrollment: 40 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• males and females, age 18 or older, enrolled in Genotype and Phenotype Registry, in general good health
• Participants who carry the genotype of interest, based on a buccal or blood derived DNA sample

Exclusion criteria

• History of Systemic Lupus Erythematosus, rheumatoid arthritis, or other autoimmune disease
• History of cancer or lymphoma
• Current use of aspirin, prednisone, or NSAID or any immunosuppressant
• Self reported HIV