The Role of Laryngopharyngeal Reflux in IPF

National Jewish Health

Status: Enrolling

Conditions: IPF; Reflux

Study type: Observational

Funder types: Other

Identifiers

NCT03418350

HS-3130

Details and patient eligibility

About

The primary objective of this study is to show that the Supraglottic Index (SGI) is an easily-collected index that accurately identifies the presence and severity of laryngopharyngeal reflux (LPF) in idiopathic pulmonary fibrosis (IPF).

Full description

The study team hypothesizes the SGI will correlate more strongly with measures of IPF severity (at baseline and over time) than gastroesophageal reflux (GER) data derived from the esophageal detector channels of a pH/impedance probe.

Enrollment: 60 estimated patients

Sex: All

Ages: 40 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of IPF
• Age 40-95
• Able to read, speak, and understand English
• If subjects are currently taking medication for reflux or GERD, they much be on a stable does for at least 4 weeks prior to consent.

Exclusion criteria

• Patients who do not meet all inclusion criteria
• Pregnant females