The Role of Microbiota in Pancreatic Cancer and Precursor Lesions (MICROPAC)

Herlev Hospital

Status: Enrolling

Conditions: Microbiome; Pancreatic Cancer

Treatments: Other: observational study

Study type: Observational

Funder types: Other

Identifiers

NCT07250100

H-22019595

Details and patient eligibility

About

This is a prospective observational study aiming to investigate the microbiome in patients suspected of having pancreatic cancer. The purpose is to enhance diagnostic accuracy by developing screening protocols for high-risk individuals, identifying specific microbial biomarkers, and improving prognostic criteria to optimize treatment response.

Participants will be asked to complete a questionnaire, provide oral and fecal swabs, and-if clinically indicated-1-2 pancreatic biopsies will be collected.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with a suspected lesion (solid/cystic) in the pancreas undergoing diagnostic or therapeutic endoscopic procedure
• Age of 18 years or above
• Signed informed consent form

Exclusion criteria

• Contraindications for endoscopic or surgical procedure, such as uncorrected coagulopathy

Trial design

300 participants in 1 patient group

Patients suspected of pancreatic cancer

Treatment:

Other: observational study