The Role of microRNA-29b in the Oral Squamous Cell Carcinoma

National Taiwan University

Status: Unknown

Conditions: Oral Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT02009852

201309076RIN

Details and patient eligibility

About

The Role of microRNA-29b in the Oral Squamous Cell Carcinoma

Full description

To find out if there is prognostic value which to the performance of microRNA-29b of oral cancer in Taiwan and provide some reference for future treatment.

We anticipate to enroll 100 persons with oral cancer and collect the tissue which was stained for pathological sections over a 3 year period.

We also collect the blood and saliva samples from patients and the results along with patient-specific information such as tumor phases, tumor size, lymph node metastasis, cancer metastasis, prognosis and betel nut chewing, smoking and drinking habits and other parameters are statistically analyzed.

Enrollment: 100 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Cancer of the oral cavity.

Exclusion criteria

• pregnant woman
• refuse the surgery

Trial design

100 participants in 1 patient group

Oral cancer

Description:

Subjects who suffer from oral cancer. Subjects must: Should have a blood exam (20ml/each time) before the surgery and 3 months after the surgery. In the case the disease recurs after the surgery, subjects need to receive the surgery again and take another blood exam before the surgery and 3 months after the surgery. Before the surgery site staff must: Collect subjects' saliva once a day (in the morning before breakfast) for 3 consecutive days. Collect a 0.5x0.5Cm2 tissue sample of the tumor during the surgery.