The Role of Mid-Life Adiposity in Functional Brain Connectivity

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Medical College of Wisconsin

Status

Terminated

Conditions

Alzheimer's Disease

Study type

Observational

Funder types

Other

Identifiers

NCT01777789
PRO16109

Details and patient eligibility

About

The purpose of the study is to use functional MRI (fMRI) to measure brain connectivity in middle-aged individuals with different levels of body fat. The ultimate goal of this research is to develop an early diagnostic tool for Alzheimer's disease.

Full description

Participants will have one visit for: Blood draw Body composition scan Cognitive screen Neurological exam MRI scan The visit will take approximately 3 hours.

Enrollment

60 patients

Sex

All

Ages

45 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 45-65 years of age
  • Normal memory
  • Right-handed
  • General good physical health

Exclusion criteria

  • History of stroke or neurological disease
  • Seizures or head injury with loss of consciousness within the last five years
  • Ferrous (magnetic) or electronic implants (due to the magnet in the MRI scanner)
  • Claustrophobia

More detailed inclusion/exclusion criteria must be met in order to qualify for the study. The study coordinator will determine eligibility.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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