The Role of No-Calorie Beverages Within a Weight Loss Program

University of Colorado Denver (CU Denver)

Status: Completed

Conditions: Obesity

Treatments: Behavioral: 2 water beverages per day; Behavioral: 2 no calorie beverages per day

Study type: Interventional

Funder types: Other

Identifiers

NCT01766700

12-1063

Details and patient eligibility

About

The no calorie drink study is looking for over 300 people to participate. The study is evaluating the effect of no calorie beverages on weight loss and weight maintained over time in people who drink diet beverages every day as compared to water only drinkers during the 1 year study period.

Full description

This investigation aims to test the hypothesis that the amount of weight lost and maintained over time in an intensive behavioral weight management program will be equivalent in subjects consuming beverages containing no calorie sweeteners as compared to water beverages.

Enrollment: 308 patients

Sex: All

Ages: 21 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Body Mass Index: 27 - 40 kg/m2
• Must drink no calorie, sweetened drinks

Exclusion Criteria

• Cardiovascular disease
• Uncontrolled blood pressure
• Smoker
• Medications that affecting metabolism
• Oral steroids
• History of stroke or seizures
• Thyroid disease
• Type 1 or 2 diabetes
• Cushings syndrome
• Renal disease
• Liver disease
• Cancer in the past 5 years
• HIV
• Active tuberculosis
• Major psychiatric disorders

Trial design

308 participants in 2 patient groups

No calorie beverages

Experimental group

Description:

2 no calorie beverages per day.

Treatment:

Behavioral: 2 no calorie beverages per day

Water

Active Comparator group

Description:

2 water beverages per day.

Treatment:

Behavioral: 2 water beverages per day