The Role of Ophthalmologic Tests and EEG Imaging in Alzheimer's Disease

Sun Yat-sen University

Status: Unknown

Conditions: Mild Cognitive Impairment

Treatments: Diagnostic Test: observational

Study type: Observational

Funder types: Other

Identifiers

NCT04277767

AD2020

Details and patient eligibility

About

Alzheimer's disease (AD) is a prevalent, long-term progressive degenerative disorder with great social impact. It is currently thought that, in addition to neurodegeneration, vascular changes also play a role in the pathophysiology of the disease. Meantime, EEG resting state has also demonstrated significant change in patients with AD in neuroscience research area. Thus, the combination of these sensitive biomarkers would lead to a potential new biomarker for detection of AD, which has higher specificity and sensitivity.

Enrollment: 60 estimated patients

Sex: All

Ages: 50 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Alzheimer's Disease

Exclusion criteria

• neurologic disorders
• psychiatric disorders

Trial design

60 participants in 3 patient groups

mild cognitive impairment (MCI)

Description:

observational

Treatment:

Diagnostic Test: observational

Patients with mild to moderate AD

Description:

observational

Treatment:

Diagnostic Test: observational

Normal controls

Description:

observational

Treatment:

Diagnostic Test: observational