The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy

Minia University Hospital

Status and phase: Enrolling; Phase 4

Conditions: Infection Wound; Antibiotic Resistant Infection

Treatments: Drug: Oral antibiotic; Drug: IV antibiotic

Study type: Interventional

Funder types: Other

Identifiers

NCT06607887

Antibiotic77

Details and patient eligibility

About

Comparison between postoperative parenteral prophylactic antibiotics, and oral antibiotics regarding the incidence of post laparoscopic cholecystectomy infection.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (aged above 18 years) undergoing laparoscopic cholecystectomy.

Exclusion criteria

• patients with comorbidities (Diabetes, malignancies, Immunosuppressed). Lost of follow-up. Patients received antibiotics within 72 hr before admission. Complicated cases involved, gangrenous and perforated cholecystitis and abscess.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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300 participants in 2 patient groups

IV antibiotic

Experimental group

Treatment:

Drug: IV antibiotic

Oral Antibiotic

Active Comparator group

Treatment:

Drug: Oral antibiotic