The Role of Probiotics in Preventing Recurrent Urinary Tract Infections in Pregnant Women

Frontier Medical and Dental College, Abbotabad

Status: Completed

Conditions: Urinary Tract Infections

Treatments: Other: Control Group; Dietary Supplement: Lactobacillus rhamnosus

Study type: Interventional

Funder types: Other

Identifiers

NCT06429358

3388

Details and patient eligibility

About

Urinary tract infections (UTIs) are a significant public health problem affecting more than 150 million people worldwide and causing a significant economic impact of approximately US$ 6 billion annually. It is one of the most common infectious diseases after upper respiratory tract infections. More than 50% of women and at least 12% of men will be affected by urinary tract infections in their lifetime. The probiotic supplement was delivered as easy-to-swallow capsules specifically prepared to maintain the viability and stability of the Lactobacillus rhamnosus GG strain throughout the research period. Participants were told to take the probiotic supplement with water to maximise absorption and efficiency, ideally after meals.

Enrollment: 30 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women aged 18-40 year
• History of recurrent urinary tract infections (two or more episodes in the past year).
• Singleton pregnancy.

Exclusion criteria

• Multiple gestations.
• History of preterm labor.
• Chronic medical conditions (e.g., diabetes mellitus, immunodeficiency disorders).
• Use of antibiotics or probiotics within the past month.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Probiotic Group

Experimental group

Description:

The probiotic group received a daily oral supplement with Lactobacillus rhamnosus. The probiotic supplement was delivered as easy-to-swallow capsules.

Treatment:

Dietary Supplement: Lactobacillus rhamnosus

Control Group

Other group

Treatment:

Other: Control Group