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The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

U

University of Manitoba

Status

Enrolling

Conditions

Burn Scar

Treatments

Procedure: pulsed dye laser

Study type

Interventional

Funder types

Other

Identifiers

NCT01488240
B2011: 074

Details and patient eligibility

About

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

Full description

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our research group is proposing the commencement of two randomized controlled trial pilot studies assessing the effects of pulsed dye laser (PDL) on burn scars. The objectives of this project will be to determine the effectiveness of pulsed dye laser therapy on burn scar vascularity, pliability, height and texture. It has been hypothesized that the PDL works on acute injury to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. Therefore the investigators are proposing to study both acute injury and late burn scars. This project will compare the effects of each laser type, and will either help support or refute the assertion that laser therapy can be used to improve burn scars.

Objectives:

To determine the benefit of pulsed dye laser treatment in improving burn scar height, texture, vascularity and pliability in acute burn injury.

Enrollment

6 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • burn scar
  • living in Winnipeg
  • scar age one to 6 months
  • Fitzpatrick I-III skin type

Exclusion criteria

  • open wound
  • active infection
  • previous scar treatment with steroid injection or interferon
  • established disposition towards keloid scarring

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

6 participants in 2 patient groups

Proximal
Active Comparator group
Description:
part of scar proximal to heart
Treatment:
Procedure: pulsed dye laser
Distal
Active Comparator group
Description:
part of scar distal to heart
Treatment:
Procedure: pulsed dye laser

Trial contacts and locations

1

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Central trial contact

Justin P Gawaziuk, MSc

Data sourced from clinicaltrials.gov

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