The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy

The University of Texas System (UT)

Status and phase: Completed; Phase 4

Conditions: Pain, Postoperative

Treatments: Drug: QL; Drug: Sham Local; Drug: Local anesthesia at incision site; Drug: Sham QL

Study type: Interventional

Funder types: Other

Identifiers

NCT05480111

HSC-MS-22-0158

Details and patient eligibility

About

The purpose of this study is to compare quality of recovery as well as peri-operative systemic opiates use and pain scores in patients undergoing laparoscopic or robotic hysterectomy when local anesthetic versus Quadratus Lumborum nerve block (QL-2) is added to the standard pain management.

Enrollment: 76 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• English or Spanish speaking
• American Society of Anesthesiologists (ASA) physical status 1-3
• Planned laparoscopic or robotic hysterectomy

Exclusion criteria

• History of chronic pain requiring preoperative opioids, Known alcoholism disorder
• Congenital coagulopathy,
• Localized soft tissue infection,
• Use of anticoagulants,
• Dementia, inability or refusal to provide consent for the surgery
• Morbid obesity (BMI > 50), due to expected technical difficulty to achieve the block

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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76 participants in 2 patient groups

QL Block

Experimental group

Treatment:

Drug: Sham Local

Drug: QL

Local Anesthesia at incision site

Active Comparator group

Treatment:

Drug: Sham QL

Drug: Local anesthesia at incision site