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The Role of Radial Peripapillary Vessel Density in Irvine-gass Syndrome (OCTA and PMCE)

F

Federico II University

Status

Completed

Conditions

Cataract
Macular Edema

Treatments

Diagnostic Test: OCTA

Study type

Observational

Funder types

Other

Identifiers

NCT06436170
05809852 Federico II

Details and patient eligibility

About

Pseudophakic cystoid macular edema (PCME), also known as Irvine-Gass syndrome (IGS), is an accumulation of fluid in the macula that occurs after cataract surgery, with an early or late presentation (cut-off 3 months) . It is the most common cause of decreased vision after uneventful phacoemulsification, with a rare incidence of 0.1-2.35% for clinically significant PCME .

Macular edema in IGS can be diagnosed and classified by optical coherence tomography (OCT), which enables its morphologic assessment. Fluorescein angiography (FA) is the gold standard to perform differential diagnosis for macular edema.

To date, OCT angiography (OCTA) has been proposed to study various retinal vascular diseases. In contrast to FA, OCTA is able to visualize Radial peripapillary vessel density (RCP).

The aim of this study was to investigate abnormalities in the vascular network of the optic nerve head in patients with IGS compared to healthy eyes, using OCT-A

Enrollment

30 patients

Sex

All

Ages

58 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Clinical diagnosis of PCME Cataract surgery

Exclusion criteria

diabetes vein occlusion uveitis vasculitis age-related macular degeneration hereditary macular dystrophy

Trial design

30 participants in 2 patient groups

30 patiens with IGS mean age 70 ±6
Treatment:
Diagnostic Test: OCTA
30 healthy controls mean age 70 ±5
Treatment:
Diagnostic Test: OCTA

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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