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The Role of Surgery for Esophageal Cancer With Metastatic Disease (M1)

National Taiwan University logo

National Taiwan University

Status

Completed

Conditions

Esophageal Cancer
Metastatic Disease

Study type

Observational

Funder types

Other

Identifiers

NCT06424210
202211084RIND

Details and patient eligibility

About

Treatment of stage IV esophageal cancer is traditionally palliative, but treatment response is usually poor. The role of surgery in the treatment of advanced esophageal cancer remains controversial. We sought to determine whether surgical treatment followed by neoadjuvant chemoradiation therapy might provide survival benefits for these patients.

A retrospective review of esophageal cancer patients with M1 disease treated at National Taiwan University Hospital was performed from April 2002 to June 2021. Patient demographics and cancer staging, treatment, and disease recurrence, and time of follow up were included for analysis. Univariate and multivariate analysis was performed for overall survival and progression-free survival analysis. Propensity score matching based on patient age and tumor staging characteristics was also performed for analysis.

Enrollment

163 patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Stage IV Esophageal Cancer patients
  • Patients were treated with chemoradiation therapy (CCRT)

Exclusion criteria

  • Not Stage IV Esophageal Cancer patients
  • Patients were not treated with chemoradiation therapy (CCRT)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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