The Role of Timed Awakening in Treatment of Enuresis

Children's Hospital Los Angeles

Status

Not yet enrolling

Conditions

Nocturnal Enuresis

Voiding Dysfunction

Treatments

Behavioral: Nightly Timed Awakening

Study type

Interventional

Funder types

Other

Identifiers

NCT06586476

CHLA-23-00080

Details and patient eligibility

About

The goal of this clinical trial is to evaluate the effectiveness of nightly timed awakening in the treatment of nocturnal enuresis in children aged 6-17. The main questions it aims to:

Determine feasibility of nightly timed awakenings
Determine the role, if any, of comorbidities on resolution of enuresis
Determine incidence of daytime accidents
Obtain patient and parental satisfaction scores

Researchers will compare a control group to treatment groups to see if there is any impact on nocturnal enuresis.

Participants will be woken up by parents in the middle of the night to use the restroom. In addition, participants will receive 30 minute psychotherapy sessions using telehealth.

Enrollment

40 estimated patients

Sex

All

Ages

6 to 17 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Our inclusion criteria are new and recently evaluated (within past 6 months) patients who are English-speaking
aged 6-17
referred to the urology clinic for enuresis (Enuresis in our study is defined as nocturnal or diurnal enuresis (more than 1 bedwetting episode/week) for greater than 3 months)

Exclusion criteria

Diagnosis of enuresis with comorbid diagnosis of diabetes mellitus (type 1 and 2), diabetes insipidus, chronic kidney disease, polyuria and/or polydipsia
Structural urologic disease (evaluated via baseline imaging)
Diagnosis of neurodevelopmental delays or conditions (i.e. celebral palsy, autism spectrum disorder) that hinders inability to follow age-appropriate instructions
Not potty trained
Improved or resolved enuresis for patients recently evaluated (within the past 6 months)
Non-English speaking
Patients currently on any over-active-bladder (OAB) medications (b3- agonists, antichloingerics) or alpha blockers for urinary symptoms (i.e. alfuzosin, tamsulosion, etc) or anti-diurectic medications for urinary symptoms (i.e.: desmopression (DDAVP))
Patients currently using bed-wetting alarms
Patients and families who are actively seeing Pediatric Clinical Urologic Psychologist.
Inability or unwillingness of individual or legal guardian/representative to give written informed consent or participate in the study