The Role of Tomotherapy in Hypofractionated/Dose Escalated Conformal Radiation Treatment for High Risk Prostate Cancer

AHS Cancer Control Alberta

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Prostate Cancer

Treatments: Procedure: Tomotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00126802

GU-06-0052/ethics 21781

Details and patient eligibility

About

Helical tomotherapy is being used to treat the prostate gland, local rates of spread and regional lymph nodes whilst sparing gross structures. The radiation to the gross disease in the prostate is hypofractionated and dose escalated. Magnetic resonance spectroscopic imaging (MRSI) is incorporated into pre- and post-treatment evaluation.

Enrollment: 60 patients

Sex: Male

Ages: Under 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• High risk localized prostate cancer

Exclusion criteria

• Low/intermediate risk, metastatic cancer
• Patient refusal

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)