The Role of Umbilical Cord Serum Therapy on Improvement of Corneal Epithelial Defect Following Diabetic Vitrectomy

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 1

Conditions: Corneal Epithelial Defect

Treatments: Drug: conventional therapy plus umbilical cord serum eye drop; Drug: conventional therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01168375

8742

Details and patient eligibility

About

80 diabetic patients underwent vitrectomy and had no history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency will be randomized into two groups (double blind)to evaluate the role of umbilical cord serum therapy on improvement of corneal epithelial defect following diabetic vitrectomy. Both groups will take the conventional medication including Chloramphenicol, Betamethasone, Cycloplegic eye drops besides the case group will take umbilical cord serum eye drop in the eye operated. After surgery the corneal epithelial defect will be measured by slit lamp.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetic patients with corneal epithelial defect following diabetic vitrectomy at labbafinejad Hospital

Exclusion criteria

• Any history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency
• Patients with one eye
• Use of any eye drops except Chloramphenicol, Betamethasone, Cycloplegic and contact lens for corneal epithelial defect

Trial design

0 participants in 2 patient groups

conventional therapy

Active Comparator group

Description:

chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours

Treatment:

Drug: conventional therapy

conventional therapy plus umbilical cord serum eye drop

Active Comparator group

Treatment:

Drug: conventional therapy plus umbilical cord serum eye drop