The Roles of Tissue Factor in Malignant Gliomas

Ontario Clinical Oncology Group (OCOG)

Status: Completed

Conditions: Venous Thromboembolism; Brain Tumors

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT00201903

OCOG-2003-TFsubstudy

Details and patient eligibility

About

To explore the relationship between tissue factor levels, tumour progression, activation of blood coagulation and venous thromboembolism with malignant glioma

Full description

To explore the relationship between tissue factor levels, tumour progression, activation of blood coagulation and venous thromboembolism with malignant glioma

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• participation in PRODIGE
• adult patients
• newly diagnosed, biopsy-confirmed grade III/IV malignant gliomas
• undergone craniotomy or stereotactic biopsy > 2 days and < 4 weeks before

Exclusion criteria

• have known hereditary thrombophilia
• are receiving experimental antiangiogenic therapy