The Safe Fast Track Study (SafeFT)

Odense University Hospital

Status

Enrolling

Conditions

Non-specific Complaints

Emergency Department

Treatments

Diagnostic Test: D-dimer

Study type

Interventional

Funder types

Other

Identifiers

NCT06219486

The SafeFT-study

Details and patient eligibility

About

Emergency departments (ED) internationally are treating an increasing number of patients.

Most require hospital services but some could be better cared for on alternative pathways.

D-dimer has some unique properties. It is non-specific and is elevated in many acute condi- tions; but conversely remains normal in the absence of significant disease. Previous studies have shown that having a normal D-dimer on arrival to the emergency department is associated with a very low risk of 30-day all-cause mortality.

The investigators propose a multicenter randomized controlled trial using D-dimer to identify patients at low risk and test if providing this information will change time to discharge disposition by the treating physician.

Enrollment

1,538 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18 or above
Able to provide oral and written informed consent in Danish
Blood tests ordered on arrival as part of standard of care
Ambulatory on arrival or walking to the ambulance (i.e., stable independent gait)
Normal vital signs (i.e., National Early Warning Score < 3)

Exclusion criteria

Unstable condition requiring immediate care in the resuscitation area
Triage level red (i.e., the most urgent patients)
Trauma (minor and major) patients
High likelihood of requiring a D-dimer analysis on clinical indications during the current hospital contact (e.g., suspected venous thromboembolic disease) that will be ordered on arrival regardless of this study
Previous participation in the study