The Safety and Efficacy Assessment of Cosmetic Products Containing Assam Tea Extracts in Volunteers.

Mae Fah Luang University

Status

Completed

Conditions

Healthy Volunteers

Treatments

Other: Cosmetic products containing 2.5% Assam tea

Other: Cosmetic products containing 0% Assam tea

Study type

Interventional

Funder types

Other

Identifiers

NCT06631859

EC 23258-17

Details and patient eligibility

About

Thailand has entered an aging society, prompting increased research on improving the elderly quality of life and preventing age-related diseases, with a particular focus on skin aging. Skin aging is linked to the degradation of dermal and epidermal tissue, leading to decreased collagen, elastin, and glycosaminoglycans, which causes reduced skin elasticity and wrinkles.

Assam tea is native to northern Thailand and is traditionally used in local products like fermented "Miang." Research shows that Assam tea contains high levels of polyphenols, particularly catechins, which have strong antioxidant properties that help combat conditions such as cancer, cardiovascular disease, and skin aging.

The study aims to study the effect of cosmetic products from Assam tea on irritation, moisturization, skin elasticity, wrinkles, and satisfaction in volunteers to enhance its value, particularly for the elderly. This effort is intended to boost the local economy, promote community-based tourism, and expand Assam tea products to national and international markets, ultimately improving livelihoods and addressing environmental concerns in northern Thailand.

Enrollment

60 patients

Sex

All

Ages

35+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Aged 35 years and older
Good physical and mental health
Willing and able to provide informed consent to participate and complete the entire duration of the study

Exclusion criteria

Women who are pregnant or breastfeeding
Presence of existing dermatological conditions
History of autoimmune disorders
Prior use of products related to wrinkle reduction or those containing active ingredients that stimulate collagen or elastin production, including topical and oral products used within the past three months (e.g., coenzyme Q10, marine extracts, pine bark extract, glutathione, and vitamin C)
Participation in any other volunteer study or program within the past three months
Use of the following medications within the past three months: contraceptives, phenytoin, hydantoin, levodopa, chloroquine, cancer chemotherapy drugs, or medications containing heavy metals
History of receiving dermatological or cosmetic procedures such as IPL (Intense Pulse Light) laser, phonophoresis, iontophoresis, laser treatments, Botox injections, fillers, or stem cell injections
Volunteers who exhibit sensitivity or irritation to the test products used in the study