The SAM Project: Science Against Malnutrition Project

Federico II University

Status

Enrolling

Conditions

Malnutrition

Treatments

Other: Data and samples collection

Study type

Observational

Funder types

Other

Identifiers

NCT06152848

2/2023

Details and patient eligibility

About

The latest data from the World Health Organization (WHO) shows that malnutrition in all its forms affects over 2.5 billion people globally. This condition is constantly increasing and affects the entire population, from childhood to the elderly. Malnutrition in all its forms negatively impacts the quality of life of patients affected and increases the risk of morbidity and mortality, as well as healthcare costs. Considering the complexity and multifactorial nature of malnutrition, the integration of multi-omics data obtained from analyzes with high-throughput technologies such as epigenomics, metagenomics, metabolomics, could benefit the prediction and evaluation of prognosis and/or response to specific treatments; this could pave the way for personalized precision medicine interventions for patients suffering from malnutrition. The SAM study aims to characterize malnutrition through the identification of specific biomarkers of the condition with the aim of developing innovative prevention and treatment programs.

Enrollment

2,000 estimated patients

Sex

All

Ages

Under 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Caucasian ethnicity;
both sexes;
age between 0 and 85 years;
affected by malnutrition due to deficiency or excess in association with other patology and sex- and age-matched healthy controls not affected by malnutrition due to deficiency or excess and any pathology
Written informed consent

Exclusion criteria