The Sarcoma Biology and Outcome Project (SarcBOP)

Prof. Dr. Richard F Schlenk

Status

Enrolling

Conditions

Sarcoma

Sarcoma of Bone and Connective Tissue

Malignant Mesenchymoma

Study type

Observational

Funder types

Other

Identifiers

NCT04758325

TMO1902

Details and patient eligibility

About

SarcBOP - An interdisciplinary and translational registry

SarcBOP aims to establish a database that integrates every aspect possibly relevant to sarcoma treatment and research. SarcBOP thus will not be limited to specific questions or patient groups, but instead will build a comprehensive database including clinical, pathologic, and radiologic information, multi-layered molecular data, and patient-reported outcomes, combined with a dedicated biobank for tissue samples and liquid biopsies. As the study integrates seamlessly with the clinical activities of the Heidelberg Sarcoma Center, the Molecular Diagnostics Program of NCT Heidelberg, including the NCT/DKTK MASTER Program, and with the NCT Trial Center, including the PMO Clinical Trials Program, SarcBOP will generate a comprehensive and continuously growing resource for clinicians, researchers, and, finally, patients.

Full description

The following data are collected and stored:

Demographics
Comorbidities
Clinical characteristics at diagnosis, relapse and progression
Radiologic images
Histological images
Treatments including DRG and OPS data, including detailed information on surgical, radiation, and medical therapy as well as treatment relevant follow-up data
Longitudinal disease assessments
Clinical outcome
Genomic, transcriptomic, epigenomic and proteomic data
Patient reported outcomes

Furthermore, biological samples are collected and processed by the Sample Processing Laboratory of the Heidelberg Center for Personalized Oncology and the NCT Biobank.

Enrollment

3,000 estimated patients

Sex

All

Ages

12+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria