The Sense of Agency (SOA)

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Status: Unknown

Conditions: Motor Tic Disorders; Motor Activity

Treatments: Other: Behavioral and fMRI

Study type: Observational

Funder types: Other

Identifiers

NCT03361332

SOA

Details and patient eligibility

About

The ability to recognize of being the actors of the behaviour and its consequences, the so-called "Sense of Agency" (SoA), is a crucial component of self-awareness. One key aspect is the distinction from a mere inference about the causality between an act and its consequences and the sense of being the agent of it. Despite a large number of behavioural studies, there is unsatisfactory evidence on the functional anatomical underpinnings of the SoA and the distinction between causality and the SoA proper. Here, the investigators use an implicit measurement of the SoA and its modulations during fMRI: the intentional binding phenomenon (IB). The ivestigators also study how the SoA and the ensuing neurophysiological correlates are modulated by the presence of a movement disorders, such as Gilles de la Tourette Syndrome.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age included between 18 and 65 years
• Right handed
• No contraindication to the fMRI exam

Exclusion criteria

• Contraindication to the fMRI exam

Trial design

50 participants in 2 patient groups

Healthy subjects

Treatment:

Other: Behavioral and fMRI

Patients with Gilles de la Tourette Syndrome

Treatment:

Other: Behavioral and fMRI