The Status of Autonomic Tone Before Tourniquet Deflation During Total Knee Replacement

Daegu Catholic University Medical Center

Status: Completed

Conditions: Hypotension; Blood Pressure, Low

Treatments: Procedure: Tourniquet deflation

Study type: Observational

Funder types: Other

Identifiers

NCT03408301

CR-13-071

Details and patient eligibility

About

This study evaluates the influences of the status of sympathovagal balance before tourniquet deflation on a decrease in arterial blood pressure following the deflation during total knee replacement arthroplasty

Full description

Patients present with different hemodynamic profiles after intraoperative tourniquet deflation during total knee replacement arthroplasty.

Sympathovagal balance can be measured before tourniquet deflation and might determine the hemodynamic response to tourniquet deflation.

Enrollment: 40 patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. American Society of Anesthesiologists physical status I - II
2. Body mass index < 35 kg/m2

Exclusion criteria

1. Coagulation deficiencies
2. Known allergies to local anesthetics
3. Neurologic deficit on the side being operated on
4. Inflammation at the lumbar puncture site
5. Cardiac conduction disorders or arrhythmias
6. Congestive heart failure
7. Serum electrolyte abnormalities
8. Psychiatric disorders
9. Patient's refusal
10. Difficulty communicating with medical personnel
11. Severe hypovolemia
12. Increased intracranial pressure
13. Severe aortic stenosis
14. Severe mitral stenosis

Trial design

40 participants in 1 patient group

Tourniquet deflation

Description:

Tourniquet deflation after insertion of the prosthetic components during total knee replacement arthroplasty under spinal anesthesia

Treatment:

Procedure: Tourniquet deflation