The Stockholm CREAtinine Measurements Project (SCREAM)

Karolinska Institute

Status: Completed

Conditions: Hypertension; Chronic Kidney Diseases; Acute Kidney Injury; Diabetes Mellitus; Cardiovascular Diseases

Treatments: Diagnostic Test: Abnormalities in specific laboratory tests; Procedure: Undertaking of specific procedures; Drug: Initiation of specific medications

Study type: Observational

Funder types: Other

Identifiers

NCT06239129

000001

Details and patient eligibility

About

The Stockholm CREAtinine Measurements (SCREAM) project is a healthcare utilization cohort including, at present, all adult residents in Stockholm between 2006 and 2021. The region of Stockholm had a population of 2.3 million citizens in 2021and provides universal healthcare with a single unified health-system. Administrative databases with complete information on socidemographic data, healthcare use, diagnoses and therapeutic/surgical procedures, and vital status were enriched with performed laboratory tests, dispensed prescriptions at Swedish pharmacies and validated kidney replacement therapy endpoints. Registries were linked and de-identified by the Swedish National Board of Welfare and are considered to have no or minimal loss to follow-up. Because the study utilized de-identified data, it was deemed not to require informed consent and was approved by the regional ethical review boards and the Swedish National Board of Welfare.

For detailed description of available data and linked registers please consult:

https://pubmed.ncbi.nlm.nih.gov/35028991/

Full description

Please consult cohort description in:

https://pubmed.ncbi.nlm.nih.gov/35028991/ https://pubmed.ncbi.nlm.nih.gov/26798472/

Enrollment: 3,200,000 patients

Sex: All

Ages: Under 110 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

For both cohorts:

Be a resident of Stockholm during 2006-2021, of all ages

For the primary cohort:

To have undertaken at least one test of serum creatinine or albuminuria during 2006-2021. If this condition is met, we will then extract a broad range of laboratory tests

For the secondary cohort:

Anyone not undertaking a test of serum creatinine or albuminuria will conform the secondary cohort. In this cohort we will not extract any other laboratory test, but will obtain the rest of healthcare information

Exclusion criteria

None