The Study of Breast MRI Screening and Proton Magnetic Resonance Spectroscopy

National Taiwan University

Status

Completed

Conditions

Breast Diseases

Treatments

Procedure: proton magnetic resonance spectroscopy

Study type

Interventional

Funder types

Other

Identifiers

NCT01749748

200806009R

Details and patient eligibility

About

To delineate if the chemical composition (lipid and water) in the presumably normal breast of the high risk women is different from those of the low risk group.

Full description

The researchers would like to investigate and compare the chemical composition in the normal breast between high risk women and general population.

Enrollment

270 patients

Sex

Female

Ages

25 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Women without breast symptoms (without family history of breast cancer; or with at least first-degree relative of breast cancer) with negative mammography and ultrasound result in recent 3 months or contralateral normal breasts from women with newly diagnosed unilateral breast cancer
25-75 years old.

Exclusion criteria

renal function impairment
past history of anaphylactoid reaction to MRI contrast media (Gd-DTPA)
pregnant or lactating women
medication of HRT or oral pills in recent 6 months
past history of surgery of the breast (either side)
past history of breast cancer
with breast implant or silicone injection
past history of cardiac surgery, mechanical valve replacement, aneurismal clip, endotracheal tube or tracheostomy tube, any metallic implants.