The Study of Personalized Health Check-up Programs and Standards for High-altitude Migrant Populations

Capital Medical University

Status: Begins enrollment this month

Conditions: High Altitude

Study type: Observational

Funder types: Other

Identifiers

NCT07018193

PHC-high

Details and patient eligibility

About

By using wearable devices to monitor and record the physiological data changes and health outcomes (incidence and severity of high-altitude illnesses) of high-altitude migrants at different stages (pre-entry, acute/chronic high-altitude phases, and de-acclimatization phase), and referencing previous cohort studies on high-altitude populations, the study aims to provide a basis for developing personalized health assessment protocols for high-altitude migrants. The formulated assessment protocols and standards will then be validated.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and women aged ≥18;
• Those living in plains and preparing to move to the plateau for a short-term or medium-term period;
• Can understand the research requirements and be willing to sign a written informed consent form (ICF).

Exclusion criteria

• Past history of contraindicated plateau travel: such as advanced COPD (FEV₁<30% of the expected value or requires continuous oxygen therapy), advanced cystic fibrosis (FEV₁<30% of the expected value or requires continuous oxygen therapy), advanced restricted pulmonary disease (FEV₁<50% of the expected value or requires continuous oxygen therapy), decompensated heart failure, high-risk pregnancy, myocardial infarction or stroke occurred within 90 days, poorly controlled epilepsy, pulmonary hypertension (PASP>90mmHg), sickle cell anemia, unstable angina pectoris, high-risk cerebrovascular abnormalities that have not been treated, etc.

Trial design

300 participants in 2 patient groups

Exploration group

Description:

200 participants, to explore and formulate and optimize personalized plans and standards for health examinations for people living in plateaus.

Verification group

Description:

100 participants, to verify the feasibility of the physical examination plan and its effectiveness in the early diagnosis of altitude sickness and plateau environment-related comorbidities.