The Synbiotics Effects in Polycystic Ovary Syndrome: A Randomized Controlled Trial (PCOS)

Maharaj Nakorn Chiang Mai Hospital

Status: Not yet enrolling

Conditions: PCOS- Polycystic Ovary Syndrome

Treatments: Dietary Supplement: synbiotics; Combination Product: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06169566

OBG-2566-0568

Details and patient eligibility

About

The goal of this clinical trial is to compare the effect of synbiotics and placebo in Thai women with polycystic ovary syndrome. The main questions it aims to answer are:

• Do synbiotics have a positive effect on the gut microbiome?
• Do synbiotics have a positive effect on reproductive outcomes?
• Do synbiotics have a positive effect on cardiovascular outcomes? Participants will be randomized, and blinded to receive either synbiotics or placebo.

While placebo is a comparison group: Researchers will compare with placebo to see if the effects on reproductive and cardiovascular risk differ.

Full description

Analysis of gut microbiome in Thai women with polycystic ovary syndrome and the synbiotics effect on reproductive and cardiovascular risk: A randomized controlled trial

Enrollment: 40 estimated patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• PCOS

Exclusion criteria

• ATB use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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40 participants in 2 patient groups, including a placebo group

Intervention

Active Comparator group

Description:

synbiotics

Treatment:

Dietary Supplement: synbiotics

non-intervention

Placebo Comparator group

Description:

placebo

Treatment:

Combination Product: placebo