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The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure

A

Armed Forces Capital Hospital, Republic of Korea

Status

Completed

Conditions

Tuberculosis

Study type

Observational

Funder types

Other

Identifiers

NCT00981071
QFTconversion

Details and patient eligibility

About

The aim is to evaluate the time of positive conversion after exposure to smear positive pulmonary tuberculosis (TB) in a platoon of Korean military, a closed communal setting.

Full description

In a platoon where TB outbreak occurred, we performed low dose chest CT (LDCT), QuantiFERON-TB gold in tube (QFT) and two-step (0, 4weeks) TST for outbreak investigation. We perform QFT at 0, 2, 4, 8 and 12 weeks after initial investigation for soldiers with negative QFT results, and soldiers with positive QFT and normal LDCT took isoniazid and rifampin for 3 months as treatment of latent TB.

Enrollment

32 patients

Sex

Male

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • All soldiers who assigned to the military platoon where a tuberculosis outbreak occurred

Exclusion criteria

  • Soldiers who could not complete study or refused the study protocol

Trial design

32 participants in 1 patient group

A platoon with TB outbreak

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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