The TOF3D Mechanomyograph. Evaluation of a New Device for Assessment of the Neuromuscular Block. (MMG versus AMG)

Klinikum Hersfeld-Rotenburg

Status: Enrolling

Conditions: Neuromuscular Blockade Monitoring; Mechanomyography

Treatments: Device: measurement of the time course of a neuromuscular block

Study type: Interventional

Funder types: Other

Identifiers

NCT07371377

MMG and TOF3D

Details and patient eligibility

About

In clinical anesthesiologic practice, most institutions use acceleromyography in order to assess the degree of a neuromuscular block.

The aim of the present study is to assess a new device using mechanomyography. Until recently, this method was reserved for experimental settings. It seems to be able to work more precisely, and additionally, it offers the opportunity to use other stimulation patterns than acceleromyographic measurements.

The investigation is divided into two parts:

Part 1 compares the mechanomyograph directly with an acceleromyograph. In part 2, two mechanomyographs using different stimulation patterns are compared with each other.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for surgery requiring general anesthesia with neuromuscular blocking agents

Exclusion criteria

• anticipated or known difficult airway
• increased risk for aspiration
• pregnancy
• neuromuscular disorders

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

comparison of mechanomyograph and acceleromyograph

Other group

Treatment:

Device: measurement of the time course of a neuromuscular block

comparison of tetanic fade versus train of four ratio

Other group

Treatment:

Device: measurement of the time course of a neuromuscular block