The Treatment of Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo (BPPV)

Asan Medical Center

Status and phase: Completed; Phase 3

Conditions: Benign Paroxysmal Positional Vertigo

Treatments: Procedure: Semont maneuver; Procedure: Modified Epley maneuver; Procedure: Reverse Epley maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT02029508

PSCC_BPPV_Kr

Details and patient eligibility

About

The purpose of this study was to compare the treatment effectiveness of three different methods for posterior semicircular canal benign paroxysmal positional vertigo. The included methods are Modified Epley maneuver, Semont maneuver and Sham maneuver.

Full description

This study was a prospective, double blinded, randomized, multicenter clinical trial. The enrolled posterior semicircular canal benign paroxysmal positional vertigo patients were randomized to one of the three treatment regimens when they are diagnosed with the Dix-Hallpike test. An then the patient was treated with one of the three maneuvers. After 20 minutes, the patient was examined with the Dix-Hallpike test again. The resolution of nystagmus and symptoms were checked. When the nystagmus was sustained, the same treatment was applied once again. And after 20 minutes, the patient was examined with the Dix-Hallpike test too. 1 day after and 7 days after, the patient was re-examined with the Dix-Hallpike test.

Enrollment: 99 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a symptom of positional vertigo
• rotational and upbeating nystagmus in Dix-Hallpike test
• the nystagmus should be disappear within 60 seconds
• no spontaneous nystagmus

Exclusion criteria

• ages under 18 years
• suspicious or verified a central nervous system lesion
• traumatic vertigo patients
• other otologic disease(acute/chronic otitis media, otosclerosis, etc)
• other vestibular disease(vestibular neuronitis, Meniere's disease, etc)
• congenital nystagmus patients
• the patients with spinal disease
• the patients with the limitation of cervical movement

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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99 participants in 3 patient groups

Epley maneuver

Active Comparator group

Description:

The group using modified Epley maneuver for PSCC BPPV

Treatment:

Procedure: Modified Epley maneuver

Semont maneuver

Active Comparator group

Description:

The group using Semont maneuver for PSCC BPPV

Treatment:

Procedure: Semont maneuver

Sham

Sham Comparator group

Description:

The group using Reverse Epley maneuver for PSCC BPPV

Treatment:

Procedure: Reverse Epley maneuver