The Treatment of Purulent Flexor Tenosynovitis

Tampere University

Status: Completed

Conditions: Tenosynovitis

Treatments: Procedure: Intraoperative flexor tendon sheath irrigation; Procedure: Postoperative flexor tendon sheath irrigation

Study type: Interventional

Funder types: Other

Identifiers

NCT02320929

R14153

Details and patient eligibility

About

This study evaluates the effect of postoperative intermittent closed-catheter irrigation on the recovery from the purulent flexor tenosynovitis. One group of patients suffering from acute purulent flexor tenosynovitis is treated using intraoperative irrigation only and the other group having both intra- and postoperative irrigation.

Full description

The foundation of the successful management of purulent flexor tenosynovitis is the surgical debridement followed by an intravenous antibiotic treatment. Several surgical methods have been described to remove the purulent debris from the flexor tendon sheath. Closed-catheter irrigation involves irrigation of the tendon sheath from proximal to distal direction facilitated by two small incisions; one proximal to A1 pulley and one distal to A4 pulley. Lille et al. (J Hand Surg Br. 2000;25(3):304-307) conducted a retrospective study that implied that intraoperative closed-catheter irrigation without postoperative irrigation might be as effective as the combination of intra- and postoperative irrigation.

The hypothesis of this prospective randomized trial is that the intraoperative closed-catheter irrigation alone is as effective as the combination of intraoperative and postoperative intermittent closed-catheter irrigation in the treatment of purulent flexor tenosynovitis.

Enrollment: 48 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical diagnosis of purulent flexor tenosynovitis with all four positive Kanavel's signs:

  • symmetric swelling of the entire digit
  • exquisite tenderness along the course of the tendon sheath
  • semiflexed posture of the digit
  • pain with attempted passive extension of the digit

• age over 18 years

• patient's willingness to participate in the study

Exclusion criteria

• High-pressure, foreign body or chemical injuries, which require open debridement
• prisoner, military serviceman, mental retardation or other factors which may affect one's decision making

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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48 participants in 2 patient groups

Intraoperative irrigation only

Experimental group

Description:

The infected tendon sheath is irrigated intraoperatively, the catheter is removed, and small rubber srains are left in small incisions.

Treatment:

Procedure: Intraoperative flexor tendon sheath irrigation

Intra- and postoperative irrigation

Active Comparator group

Description:

The infected tendon sheath is irrigated intraoperatively, the catheter is kept in place, the irrigation is continued postoperatively 3 times a day for 3 days.

Treatment:

Procedure: Postoperative flexor tendon sheath irrigation

Procedure: Intraoperative flexor tendon sheath irrigation