The Use of Cyanoacrylate on Palatal Wound

T.C. ORDU ÜNİVERSİTESİ

Status: Completed

Conditions: Gingival Recession

Treatments: Procedure: Free gingival graft; Procedure: Cyanoacrylate application

Study type: Interventional

Funder types: Other

Identifiers

NCT03273010

Ordu Uni

Details and patient eligibility

About

The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative complaints.

Full description

A total of 35 patients were included in the study. In the test group (19 patient), cyanoacrylate was placed over the palatal wounds; conversely, the 16 control group patients were allowed to heal in a conventional way without cyanoacrylate.

Primary bleeding time, presence of secondary bleeding, postoperative pain and completion of epithelization were assessed following free gingival graft operation. As a result, compared to the control group it was determined that the cyanoacrylate tissue adhesive could reduce the postoperative morbidity and improve the wound healing.

Enrollment: 35 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• no systemic diseases
• no coagulation disorders
• no drug intake in the previous 6 months that might effect the periodontal health status
• no pregnancy or lactation
• no smoking habit
• <1 mm attached gingiva width on one or two lower anterior teeth
• Miller Class I- II- III (Miller 1985) with deep gingival recession (˃ 3mm)

Exclusion criteria

• Hematologic disorders
• No cooperation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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35 participants in 2 patient groups

Periacryl group

Experimental group

Description:

Periacryl, a tissue adhesive, was applied on wound surfaces to achieve haemostasis

Treatment:

Procedure: Free gingival graft

Procedure: Cyanoacrylate application

Control group

Active Comparator group

Description:

Free gingival graft was harvested from palatal region and left to heal without applying periacryl.

Treatment:

Procedure: Free gingival graft