The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation
Status
Withdrawn
Conditions
Tooth Loss
Treatments
Other: Autogenous dental pulp tissue
Other: Resorbable collagen membrane
Other: Particulate bone graft
Other: Suture
Details and patient eligibility
About
The purpose of this study is to examine and compare the effects of autogenous dental pulp tissue on bone formation in the extraction sockets as compared to commonly used particulate bone graft. The effects on bone formation will be examined using a wide variety of assays.
Sex
All
Ages
18+ years old
Volunteers
Accepts Healthy Volunteers
Inclusion criteria
- American Society of Anesthesiologists (ASA) Physical Status Classification System ASA 1 (A normal healthy patient) or ASA 2 (A patient with mild systemic disease)
- never smoker
- patients with planned tooth extraction
- intact extraction sockets
- no medication or antibiotics intake for at least 6 months prior to the procedure
- patients who gave their consent to participate in the study.
Exclusion criteria
- vulnerable subjects (children, pregnant and lactating women, patients with learning disabilities, and prisoners)
- inability to obtain pulp tissue (for example, due to previous endodontic therapy, obliterated pulp canals)
Trial design
Primary purpose
Treatment
Allocation
Randomized
Interventional model
Parallel Assignment
Masking
Double Blind
0 participants in 2 patient groups
Particulate bone graft plus autogenous dental pulp tissue
Experimental group
Description:
Dental pulp will be isolated from teeth extracted for non-periodontal reasons chairside. The isolated dental pulp will be mixed with hydrated particulate bone graft, and the mixture will be placed in the debrided extraction socket. The socket will be covered by a resorbable collagen membrane and sutured.
Treatment:
Other: Resorbable collagen membrane
Other: Suture
Other: Particulate bone graft
Other: Autogenous dental pulp tissue
Particulate bone graft
Active Comparator group
Description:
Hydrated particulate bone graft will be placed in the debrided extraction socket. The socket will be covered by a resorbable collagen membrane and sutured.
Treatment:
Other: Resorbable collagen membrane
Other: Suture
Other: Particulate bone graft
Trial contacts and locations
1
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Data sourced from clinicaltrials.gov
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