The Use of Manuka Honey to Improve Healing After Third Molars Surgery

Damascus University

Status: Completed

Conditions: Surgical Extraction of Impacted Third Molars

Treatments: Biological: Manuka Honey

Study type: Interventional

Funder types: Other

Identifiers

NCT02483741

UDDS-OMFS-04-2015

Details and patient eligibility

About

Since there is an evidence that Manuka honey is an antibacterial agent, the present study aims to confirm this characteristic and assess its effect in improving healing and reducing postsurgical symptoms, if topically applied after the surgical removal of impacted mandibular third molars

Full description

Sufficient evidence exists recommending the use of honey in the management of acute wounds and burns. Studies revealed that the healing effect of honey could be classified by its antibacterial, antiviral, anti-inflammatory and antioxidant properties of its components. Manuka honey has been shown to inhibit a wide range of microorganisms, including multiresistant strains. This unique honey is derived from flowers of manuka tree (Leptospermum scoparium) in New Zealand. Dihydroxyacetone and methylglyoxal are unique and naturally occurring constituents of manuka honey that correlate with its antibacterial activity.

Since surgical extraction of impacted molars is one of the most common operations in the oral cavity and the postoperative symptoms disturbing the patient may reduce the quality of health service, this study aims to assess the healing potential of Manuka honey in reducing these symptoms by comparing the outcome of extraction of impacted lower molars with and without topical application of Manuka honey into the extraction socket.

Enrollment: 50 patients

Sex: All

Ages: 20 to 37 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Asymptomatic, Symmetrical, Bilateral Impacted Third Molars

Exclusion criteria

• Uncontrolled diabetes,
• Hypersensitivity to Honey
• Alcoholism,
• Drug abuse,
• Pathological condition in the region

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Manuka Honey

Experimental group

Description:

Manuka Honey will be placed in the sockets of the extracted third molars in this group

Treatment:

Biological: Manuka Honey

Traditional Extraction

No Intervention group

Description:

No any special material will be placed in the sockets of the extracted third molars in this group