The Use of Narrow Band Imaging in Screening Colonoscopy

Valduce Hospital

Status: Completed

Conditions: Colonoscopy

Treatments: Procedure: Narrow Band Imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT00908648

NBI-01

Details and patient eligibility

About

Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.

Enrollment: 206 patients

Sex: All

Ages: 50 to 69 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50-69 year-old asymptomatic subjects at average-risk of CRC
• positive FOBT participating in a national mass-screening program and referred for colonoscopy

Exclusion criteria

• ongoing anticoagulation therapy
• inadequate bowel cleansing
• incomplete colonoscopy
• refusing to participate

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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206 participants in 2 patient groups

1

No Intervention group

Description:

standard white light

2

Experimental group

Description:

Narrow Band Imaging

Treatment:

Procedure: Narrow Band Imaging