The Use of Perfusion CT Derived Parameters as Early Acute Pancreatitis Severity Biomarker Compared to Clinico Biological Score (K-PA)

Poitiers University Hospital

Status: Completed

Conditions: Acute Pancreatitis

Treatments: Radiation: Perfusion computed tomography.

Study type: Interventional

Funder types: Other

Identifiers

NCT03456557

K-PA Study

Details and patient eligibility

About

The investigators to establish whether early microvascular permeability parameter evaluated by perfusion-CT could be good biomarkers for severity in acute pancreatitis.

Therefore the investigators want to compare 48 hours-clinico-biological systemic inflammatory response syndrome score to initial microvascular permeability parameters ( ktrans - capillary membrane permeability factor- and pancreatic blood flow ) calculated by OLEA software using inclusion perfusion CT.

Enrollment: 15 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with acute pancreatitis (based on the Atlanta definition).

Exclusion criteria

• Patient under 18 yearras old
• Contraindication of injection of iodinated contrast medium
• Pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Computed tomography.

Experimental group

Treatment:

Radiation: Perfusion computed tomography.