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The Use of Repetitive Magnetic Stimulation for Strength Training of the Quadriceps Muscle

Imperial College London logo

Imperial College London

Status

Completed

Conditions

Chronic Obstructive Pulmonary Disease

Treatments

Device: Repetitive magnetic stimulation to the quadriceps

Study type

Interventional

Funder types

Other

Identifiers

NCT00159367
EU QLRT-2001-2285
RR1

Details and patient eligibility

About

We intend to use repetitive magnetic stimulation to the quadriceps muscle to try to improve strength and improve the metabolic function of the muscle.

Full description

Quadriceps strength is reduced in COPD. Increasing quadriceps strength is one of the goals of pulmonary rehabilitation yet some patients with severe COPD are unable to exercise with sufficient intensity, due to breathlessness, to achieve a true training benefit.

Transcutaneous electrical stimulation of the femoral nerve has been shown to improve quadriceps muscle strength, muscle mass, and performance in patients with severe COPD. Magnetic stimulation may be preferred because it offers the opportunity to train the whole muscle and because it is painless. In this pilot study we are investigating whether repetitive magnetic stimulation camn increase the strength of the quadriceps muscle and whether it confers any change in structure or metabolism of the muscle itself.

Enrollment

20 estimated patients

Sex

All

Ages

40 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Chronic Obstructive Pulmonary Disease

Exclusion criteria

Aspirin therapy Cardiac Pacemaker

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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