The Use of Stromal Vascular Fraction for Knee Arthrosis

Ghent University Hospital (UZ)

Status: Enrolling

Conditions: Knee Arthrosis

Treatments: Procedure: Injection of SVF in fat pad of the knee

Study type: Interventional

Funder types: Other

Identifiers

NCT06171204

BC-07772

Details and patient eligibility

About

A trial to investigate the safety and efficacy of SVF for the treatment of knee arthrosis.

Patients will undergo a single liposuction to obtain the SVF. The SVF will then be isolated and frozen in our laboratory. The SVF will then be injected up to 2 times into the fat pad of the patient's knee.

Full description

Stromal Vascular Fraction (SVF) from adipose tissue is increasingly being used in the clinic for a variety of conditions (skin disorders, joint pain, etc.). SVF is a collective term for cells that can be obtained from liposuction fat. These cells can be separated from the fat by mechanical processing of the liposuction fat combined with an additional centrifugation.

Despite the fact that enough SVF can be isolated after such a liposuction for multiple treatments (>3), our research group has found a way to safely freeze SVF without significant loss of SVF cells. In this way, a patient would only have to undergo one liposuction and associated anesthesia to be able to obtain multiple SVF treatments.

Enrollment: 10 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Legal capacity
• Osteochondral lesions
• Inflammatory complaints
• (Peri)tendinitis or tendinopathies and ligamentous injuries
• Impingement complaints
• Arthrofibrosis
• Anterior knee pain

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)