The Utility of Platelet Rich Plasma in Hair Loss

University of California Irvine (UCI)

Status and phase: Completed; Early Phase 1

Conditions: Androgenetic Alopecia

Treatments: Procedure: Platelet rich plasma

Study type: Interventional

Funder types: Other

Identifiers

NCT03376581

20163239

Details and patient eligibility

About

Platelet rich plasma (PRP) is an autologous preparation of human plasma with high concentration of platelets. Platelets release numerous growth factors, which stimulate cell proliferation and differentiation.

The purpose of this research is to investigate the potential of PRP injection for treatment of hair loss. Clinical outcomes will be assessed by noninvasive techniques including dermoscopy, multiphoton microscopy, optical coherence tomography, optical Doppler tomography and multispectral imaging.

Enrollment: 30 patients

Sex: All

Ages: 18 to 95 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Over 18 years of age
• Ability to understand and carry out instructions
• Diagnosed with alopecia

Exclusion criteria

• Inability to understand and.or carry out instructions
• Pregnant women
• Use of any topical medication (such as minoxidil or any other solution for hair growth), oral medication (finasteride, dutasteride, or antiandrogens), laser therapy, or chemotherapy, within the preceding 4 weeks.
• Personal medical history of bleeding disorders
• Personal medical history of platelet dysfunction syndrome
• Anti-coagulation therapy or nonsteroidal anti-inflammatory drugs in the last 1 week.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Prospective treatment

Experimental group

Treatment:

Procedure: Platelet rich plasma