The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position

Yonsei University

Status: Completed

Conditions: General Anesthesia

Treatments: Procedure: Fluid infusion

Study type: Interventional

Funder types: Other

Identifiers

NCT02771067

4-2016-0205

Details and patient eligibility

About

The purpose of this study is to investigate the validity of pulse pressure variation to predict fluid responsiveness in patients undergoing robotic or laparoscopic gastrectomy.

Enrollment: 30 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients aged over 19 years who are scheduled for robotic or laparoscopic gastrectomy

Exclusion criteria

• cardiac arrhythmia
• valvular heart disease
• ischemic heart disease
• left ventricular ejection fraction less than 40%
• Pulmonary disease
• esophageal disease
• upper gastrointestinal bleeding
• Body mass index more than 40 kg/m2.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Pulse pressure variation

Experimental group

Description:

Pulse pressure variation will be recorded via an arterial catheter after anesthetic induction, before pneumoperitoneum, after pneumoperitoneum, before infusion of 6% hydroxyethyl starch, and after infusion of 6% hydroxyethyl starch. Stroke volume will be also measured to differentiate the fluid responders.

Treatment:

Procedure: Fluid infusion